Geneious 生物信息學數據分析軟體

Geneious 生物信息學數據分析軟體

FCS Express 流式細胞術軟體PostSharp 程式優化工具

£100.00

Geneious軟體包含您的組織所需的所有分子生物學和序列分析工具。無論您是希望提高生產力、增加可見性和洞察力，還是減少錯誤和風險——我們的平台都能釋放您實驗室數據的價值。

貨號: Geneious-1 分類: 標籤: , ,

描述

Geneious 生物信息學軟體

Geneious Prime 產品特色

NGS Pre-Processing

  • Import Illumina, PacBio and NanoPore reads
  • Trim, filter and demultiplex both single-end and paired-end data
  • Merge paired reads
  • De-duplicate
  • Error correct and normalize
  • Filter out chimeras

Mapping and de novo Assembly

  • Simply switch between industry leading algorithms for mapping and de novo assembly
  • Support for assembly of Sanger and NGS data, including Illumina, PacBio and Oxford Nanopore reads of any length, including paired-end reads and hybrid assemblies
  • Produce circular contigs when assembling microbial genomes, plasmids and other circular sequences
  • Genome comparison and finishing with MAUVE genome alignment
  • Mappers including Geneious, Geneious for RNA Seq, BBMap, Minimap2, Bowtie2 and TopHat
  • De novo assembly algorithms including Geneious, SPAdes, Flye, MIRA, Tadpole and Velvet

Variant Calling and Expression Analysis

  • Call SNPs/variants using Geneious or FreeBayes
  • Perform real-time filtering of tabular results with synchronized genome view
  • Calculate and compare expression levels on mapped RNA-seq data
  • Visualize using PCA and volcano plots

Sequence Analysis

  • Trim, assemble, and view Sanger sequencing trace files
  • Correct base calls and create consensus sequences
  • Annotate motifs, ORFs and repeats
  • Predict genes and structural elements
  • Real-time annotation via similarity search against database
  • Translate selections on the fly, or show translation for annotations or selected frame
  • Dynamic graphs and statistics for sequence properties such as pI, molecular weight, melting point, AA composition and more

Sequence Alignment

  • Multiple and pairwise sequence alignment of DNA or protein including full genome alignment
  • Align with trusted algorithms including Geneious Aligner, MUSCLE, MAFFT, Clustal Omega, MAUVE and LastZ
  • View and edit alignments with real-time translation and highlighting

Phylogenetics

  • Build trees with Geneious tree builder, MrBayes, PAUP*, PhyML, RAxML and more
  • Visualize, edit and markup your trees
  • Interactive distance matrix viewer
  • Publication quality export

Microsatellite Analysis

  • Import raw ABI trace files
  • Trim, predict and manually adjust peaks
  • Bin peaks into alleles
  • Produce tabular output of allele calls

Molecular Cloning

  • View plasmid maps, automatically annotate vectors, and copy-paste sequences with annotations
  • One-step GoldenGate (Type IIS) and Restriction cloning
  • Homology-based cloning including Gibson, GeneArt, and In-Fusion
  • TOPO cloning
  • Parent/descendant lineage tracking of cloning operations
  • Codon optimization and back translation
  • Silent mutation analysis to find potential restriction sites to introduce
  • CRISPR gDNA design
  • Simulated PCR, digestion and ligation

Primer Design

  • Automatically design PCR and sequencing primers and hybridization probes, to any target region or entire sequence
  • Easily add primers in the Sequence View
  • Design basic and degenerate PCR primers
  • Add and remove extensions to a primer sequence before, during or after the design process
  • Primer specificity testing to check for additional binding sites on the template sequence
  • Screen for physical properties, hairpins and primer-dimers
  • Drag and drop your primers in FASTA, spreadsheet or GenBank format

Data Management and Collaboration

  • Drag and drop import of files and folders, including Vector NTI databases
  • Import metadata from a spreadsheet onto sequences and other documents
  • Smart NGS import – one step import of any assortment of SAM, BAM, GFF, BED, and VCF files
  • Intuitive folder-based project organization
  • Seamlessly integrated shared database
  • Rapid search against all sequences and metadata in your database
  • Extensive export options

Searching and BLAST

  • Direct access to NCBI public BLAST databases
  • Custom BLAST for private local databases
  • Integrated search of external databases including GenBank and UniProt
  • Upload your sequences directly to GenBank
  • Search for literature in PubMed
  • Advanced searching against your local or shared database

Automated Workflows

  • Create workflows for automated bulk analysis using a visual editor
  • More than 20 in-built workflows for performing pipelines including Apply Variants to Reference Sequence, Map Reads then find SNPs, and Randomly Sample Sequences
  • Extend capabilities with option to write custom code workflows

API & Developers

  • Add specialized functionality or integrate with other systems using the Plugin Development Kit
  • Add your favorite algorithm, database or visualization
  • Wrap a command line program to run via the Geneious Prime GUI

 

Geneious Biologics 產品特色

Annotate and Analyze

  • Efficiently analyze Sanger and NGS datasets
  • Annotate CDR/FR Regions from germline or custom databases
  • Highlight sequence features, assets, and liabilities
  • Annotate various antibody types including mAb, Fab, scFv, VHH, TCR, and VH/ VL pairs

Identify Statistical Trends

  • Cluster sequences by regions or clonotype
  • Identify dominant clones
  • Group functionally similar sequences
  • Compare frequencies across samples

Visualize and Discover

  • Integrate assay data
  • Search and filter using powerful queries
  • View interactive graphs, trees, and alignments
  • Build reports with tables, graphs and comments

Manage Data

  • Collaborate with team members and share results
  • Search for sequences in a central database
  • Import and export data seamlessly
  • Access a secure and reliable cloud computing platform

Highly Configurable

  • Connect important in-house tools, including LIMS, to Geneious Biologics
  • Directly share files with Geneious Prime

 

版本比較

版本比較

Geneious Prime

Group Subscriptions

The best option for teams of any size.

Your group subscription includes:

  • Free upgrades, updates and fixes during the term of your subscription
  • Purchase Geneious Prime for additional activations at any time at a
    prorated rate
  • Ability to deploy with conventional IT tools for large groups
  • Automatic renewal without need for re-installation or re-activation
  • Cross-platform: Windows, Mac and Linux
  • Active support for technical issues, set up and training

Personal Subscriptions

1 year subscription plans for individual use.

Your personal subscription includes:

  • Free upgrades, updates and fixes during the term of your subscription
  • Automatic renewal without need for re-installation or re-activation
  • Cross-platform: Windows, Mac and Linux
  • Active support for technical issues, set up and training

Geneious Biologics

Annual Subscription Plans

Personal

Premium antibody discovery and analysis solution for individual users

✓ Single user

✓ Annotation of IgG-like molecules

✓ Analysis of up to 24 sequences

✓ Visualizations with sequence viewer

✓ Access to results for 7 days

✓ Annotate Fab, VHH, scFv, TCR and more

✓ Analyze and filter millions of sequences

✓ Advanced statistics and graphics

✓ Single cell analysis

✓ Alignments and trees with incorporated  assay data

Group

Premium antibody discovery and analysis solution for teams

✓ Single user

✓ Annotation of IgG-like molecules

✓ Analysis of up to 24 sequences

✓ Visualizations with sequence viewer

✓ Access to results for 7 days

✓ Annotate Fab, VHH, scFv, TCR and more

✓ Analyze and filter millions of sequences

✓ Advanced statistics and graphics

✓ Single cell analysis

✓ Alignments and trees with incorporated  assay data

✓ Unlimited users

✓ Share and collaborate on results

✓ Advanced user administration

系統需求

Minimum system requirements for running Geneious Prime

This depends greatly on the type of work you will be using Geneious Prime for, but we recommend at least the following:

  • Operating System: See Supported Operating Systems
  • Processor: x86 64-bit
  • Memory: 2GB or more
  • Hard-disk: 2GB or more of free space
  • Video: 1024×768 resolution or higher

Supported Operating Systems

Windows:

Supported Windows operating systems vary depending on the version of Geneious you are running, as follows:

Geneious Prime 2025 and later: Windows 10 (Version 1803+) and 11.

Geneious Prime 2024 and earlier: Windows 7, 8, 8.1, 10 and 11.

Notes:

  • 32-bit and ARM-based Windows is not supported
  • The following plugins are not supported on Windows: TopHat, Velvet Optimiser
  • The following plugins require Windows subsystem for Linux to be installed (Ubuntu 22.04 – see WSL setup for details): Spades, Flye, and STAR
  • Insider Program and Long-term servicing channel are not supported

Linux:

Geneious R10 and higher:  Ubuntu Desktop LTS (22.04, and 24.04).

Geneious R9 and earlier: Ubuntu Desktop LTS 16.04

Notes:

MacOS:

Supported Apple operating systems vary depending on the version of Geneious you are running, as follows:

Geneious Prime 2024-2025: MacOS 12.7 and higher

Geneious Prime 2023: MacOS 10.14 and higher

Geneious Prime 2020-2022: MacOS 10.11 and higher.

Geneious Prime 2019: MacOS 10.8 – 10.15*

Geneious R10 and R11:  MacOS 10.8 – 10.14

Geneious R9: MacOS 10.6 – 10.14.  Users on OS 10.6 will need to install Java 6 from https://support.apple.com/kb/dl1573

Geneious 5.5-8.1:   Mac OS 10.6 – 10.11, requires installation of Java 6 from https://support.apple.com/kb/dl1573 (10.6) or http://support.apple.com/kb/DL1572 (10.7-10.11)

*Only Geneious Prime 2019.2.3 is fully compatible with MacOS Catalina.  Users on R9-R11 may be able to get Geneious working on these later Mac operating systems by downloading the Catalina Licensing Fix but may still encounter errors with some operations.  See this post for further information.

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